Introduction
Green tea infusion has long been recognized as a healing drink. Traditional
Chinese medicine claims that green tea improves blood flow, relieves joint
pain, strengthens immunity and detoxifies the body. Modern medical research
proves the healing properties of tea in relation to developing cancer,
neurodegenerative diseases, atherosclerosis and obesity. Green tea is rich in
polyphenolic compounds from the group of flavanols, flavonoids,
proanthocyanidins and phenolic acids. Green tea is mainly grown in China, Japan
and Taiwan, and to a lesser extent also in India.
Chemical composition and health effects
The chemistry of green tea is very similar to that of freshly plucked leaves, except for a few enzymatic changes that occur rapidly after the leaves are plucked. Freshly picked leaves contain 30-40% polyphenols, 17% protein, 4% caffeine and 27% fiber, and small amounts of β-carotene, vitamins B, D and ascorbic acid. Green tea contains vitamin C which is destroyed by the fermentation process. The polyphenols in green tea are more known as flavonoids or catechins, represent
30-40% of
the soluble substances of green tea leaves. Flavonoids are found in all parts
of plants, especially in photosynthetic cells, and are an integral part of
human and animal diets. The high chemical activity of flavonoids is related to
the binding of polymers and heavy metal ions and the ability to catalyze the
transport of electrons and scavenge free radicals. Tea contains 200 to 300 mg
of flavonoids in 1 cup.
Catechin is
a type of tannin that is specific to green tea. Tannins are polyphenols, have
an astringent flavor, and can be found in several thousand types in plants. As
many as 2,000 of them are known to form a flavonoid structure and are called
flavonoids. Catechin is one of them. There are 4 main catechins in green tea
that differ in their degree of antioxidant effectiveness. They are:
epigallocatechin gallate (EGCG), epicatechin gallate (ECG), epigallocatechin
(EGC) and epicatechin (EC). EGCG is the most powerful catechin. EGCG acts as an
antioxidant 25 times more powerful than vitamin E and 100 times stronger than
vitamin C. A cup of green tea can provide 10–40 mg of polyphenols and has a
stronger antioxidant effect than a serving of broccoli, spinach, carrots or
strawberries. The high antioxidant activity of tea has a benefit by protecting
against oxidative damage caused by free radicals.
Species |
polyphenols
(in g/100 g dry weight
of leaves) |
Tannin |
Caffeine |
||||
catechin |
EC |
EGC |
ECG |
EGCG |
|||
C. sinensis var. sinensis |
0,07 |
1,13 |
2,38 |
1,35 |
8,59 |
1,21 |
2,78 |
C. sinensis var. assamica |
0,02 |
1,44 |
0,035 |
3,35 |
12,10 |
1,43 |
2,44 |
Catechins
react with toxins formed by harmful bacteria (mainly those belonging to the
protein family) and harmful metals such as lead, mercury, chromium, and
cadmium, breaking them down.
The health
benefits of consuming catechins are as follows:
- they
eliminate free radicals, preventing the growth of cancer cells by blocking the
growth of substances that cause cancer. It also stops the aging process.
- combine
with cholesterol, absorb it and block it, thus lowering its level in the blood.
They also prevent the formation of bad cholesterol caused by oxidation, which
prevents blood vessels from constricting due to the accumulation of this
cholesterol,
- prevent
arteriosclerosis, thrombosis, heart attacks and brain injuries,
- they
effectively reduce high blood pressure,
- they
block the action of enzymes that absorb and absorb sugar, preventing diabetes,
- they
fight bacteria and viruses and prevent flu, food poisoning and caries,
- improve
intestinal peristalsis, stopping the proliferation of harmful bacteria and increasing
the number of bacteria needed,
- combine
with various substances (contained, for example, in fish, meat, etc.),
preventing unpleasant odors,
- they
change harmful ultraviolet radiation into harmless light in plants, thus
protecting them.
Tea polyphenols
act as antioxidants to eliminate reactive oxygen and nitrogen (nitrosyl)
radicals as well as chelators of active metal ions in the redox system. Both
radicals and active metal ions are very toxic because they destroy lipids,
proteins and nucleic acids.
As
antioxidants that reduce the formation of free radicals in the body,
polyphenols can also indirectly influence the inhibition of pro-oxidative
enzymes such as induction nitric oxide synthetase, lipoxygenase, cyclooxygenase
and xanthine oxidase. Bacterial endotoxins as well as pro-inflammatory
cytokines stimulate macrophage expression of the inductive isoform of nitric
oxide synthetase, resulting in the formation of large amounts of active nitric
oxide. Nitric oxide reacts spontaneously with superoxide to form peroxynitrite
and other oxidants which destroy DNA and proteins. Both green and black tea, as
well as individual catechins and theaflavins, have the ability to inhibit both
the expression and activity of iNOS in macrophages. Green tea catechins and
theaflavins in black tea inhibit iNOS by blocking the activity of the nuclear
factor-kB.
Cellular
antioxidants not only eliminate reactive radicals directly, they also induce
the expression of genes encoding the synthesis of defense proteins, such as
glutathione peroxidase, gammaglutamylcysteine synthetase, NAD (P) H: quinone
reductase, or heme oxygenase-1, among others. EGCG, the quantitatively dominant
catechin in green tea, has been shown to inhibit DNA oxidative damage and
cytotoxicity caused by tobacco nitrosamine, which causes lung cancer. A similar
preventive effect of EGCG was observed with respect to the photocarcinogenic
effect of UV radiation on the skin. The anti-cancer effect of EGCG was
correlated with a reduction in the production of free radicals, reduced lipid
peroxidation and maintenance of intracellular glutathione activity. Moreover,
EGCG influences the restoration of detoxification enzymes such as glutathione
S-transferase, glutathione peroxidase, superoxide dismutase, and catalase.
Although these observations confirm the effect of EGCG on stimulating the
antioxidant defense mechanisms of the cell, limiting the possibility of
carcinogenesis, they reveal only one of the mechanisms of possible action of
tea catechins on the body.
Drink it the best tea for health!
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